黄疸（Jaundice）：
黄疸是胰腺癌重要症状。黄疸属于梗阻性，伴有小便深黄及陶土样大便，虽症状可以有轻微波动，但不可能完全消退。黄疸的暂时减轻，在早期与壶腹周围的炎症消退有关，晚期则由于侵入胆总管下端的肿瘤溃烂腐脱所致，有些胰腺癌病人晚期出现黄疸是由于肝转移所致。
Jaundice is an important symptom of pancreatic cancer. It is obstructive in nature, accompanied by dark yellow urine and clay-colored stools. Although the symptoms may fluctuate slightly, they cannot be completely resolved. The temporary relief of jaundice in the early stage is related to the resolution of inflammation around the ampulla of Vater, while in the late stage, it is caused by the necrosis and sloughing of the tumor invading the lower end of the common bile duct. In some patients with pancreatic cancer, jaundice in the late stage is due to liver metastasis.

消化道症状（Gastrointestinal Symptoms）：
最多见的为食欲不振，恶心、呕吐，可有腹泻或便秘甚至黑便。食欲不振和胆总管下端及胰腺导管被肿瘤阻塞，胆汁和胰液不能进入十二指肠有关。胰腺的梗阻性慢性胰腺炎导致胰腺外分泌功能不良，也必然会影响食欲。少数病人出现梗阻性呕吐，约10%病人有严重便秘。胰腺癌也可发生上消化道出血，表现为呕血、黑便。
The most common gastrointestinal symptoms include loss of appetite, nausea, and vomiting, with possible diarrhea, constipation, or even melena. The loss of appetite is related to the obstruction of the lower end of the common bile duct and pancreatic duct by the tumor, preventing bile and pancreatic juice from entering the duodenum. Obstructive chronic pancreatitis caused by the tumor leads to impaired exocrine function of the pancreas, which inevitably affects appetite. A few patients experience obstructive vomiting, and about 10% of patients have severe constipation. Pancreatic cancer can also cause upper gastrointestinal bleeding, manifesting as hematemesis and melena.
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消瘦、乏力（Weight Loss and Fatigue）：
胰腺癌和其他癌不同，常在初期即有消瘦、乏力。
Unlike other cancers, pancreatic cancer often presents with weight loss and fatigue in the early stage.
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腹部包块（Abdominal Mass）：
胰腺在于后腹部，较难摸到。腹部包块系癌肿本身发展的结果，位于病变所在处，如已摸到肿块，多属进行期或晚期。
The pancreas is located in the posterior abdomen and is difficult to palpate. An abdominal mass is the result of the development of the cancer tumor itself, located at the site of the lesion. If a mass is palpable, it is mostly in the progressive or advanced stage.
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症状性糖尿病（Symptomatic Diabetes）：
少数病人起病的最初表现为糖尿病的症状，即在胰腺癌的症状出现以前，先患糖尿病，以至伴随的消瘦和体重下降被误为是糖尿病的表现。若长期患糖尿病的病人近来病情加重，或原来长期能控制病情的治疗措施变为无效，说明有可能在原有糖尿病的基础上又发生了胰腺癌。
A few patients initially present with symptoms of diabetes, i.e., they develop diabetes before the onset of pancreatic cancer symptoms, leading to accompanying weight loss and decreased body weight being misinterpreted as manifestations of diabetes. If a patient with long-standing diabetes experiences worsening of their condition recently, or if previously effective treatment measures become ineffective, it may indicate the development of pancreatic cancer on top of the existing diabetes.
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血栓性静脉炎（Thrombophlebitis）：
晚期胰腺癌患者出现游走性血栓性静脉炎或动脉血栓形成。
Patients with advanced pancreatic cancer may develop migratory thrombophlebitis or arterial thrombosis.

精神症状（Psychiatric Symptoms）：
部分胰腺癌患者可表现焦虑、急躁、抑郁、个性改变等精神症状。
Some patients with pancreatic cancer may exhibit psychiatric symptoms such as anxiety, irritability, depression, and personality changes.

腹水（Ascites）：
一般出现在胰腺癌的晚期，多为癌的腹膜浸润、扩散所致。腹水可能为血性或浆液性，晚期恶病质的低蛋白血症也可引起腹水。
Ascites generally occurs in the late stage of pancreatic cancer, mostly due to peritoneal infiltration and diffusion of the cancer. Ascites may be serosanguinous or serous, and it can also be caused by hypoproteinemia in advanced cachexia.